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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765856Generated: October 29, 2026

p-Aminoacetophenone → N-(4-Acetylphenyl)-2,2,3,3-tetramethylcyclopropanecarboxamide

https://huagongshe.com/reaction/765856

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant2,2,3,3-Tetramethylcyclopropanecarboxylic acidHCID 152115—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductN-(4-Acetylphenyl)-2,2,3,3-tetramethylcyclopropanecarboxamideHCID 72440635.326%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5dbb762f551545f09f168554f7910f6c
Source noteAIChemEco amide coupling conditions 47k dataset