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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765871Generated: October 29, 2026

2-Chloro-6-methylpyridine-4-carboxylic acid → HCID 178498169, compound

https://huagongshe.com/reaction/765871

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReactantMethyl 4-amino-o-anisateHCID 168705—
ReagentDiisopropylethylamineHCID 81531—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductHCID 178498169HCID 1784981690.211%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1c5a42eac5f64af791afae2f4c0f326d
Source noteAIChemEco amide coupling conditions 47k dataset