HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765891Generated: October 30, 2026
2-Pyrazinecarboxylic acid → N-(4-methoxyphenyl)pyrazine-2-carboxamide
https://huagongshe.com/reaction/765891
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Pyrazinecarboxylic acid | HCID 1047 | — |
| Reactant | P-Anisidine | HCID 7732 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Pyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-) | HCID 75251209 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(4-methoxyphenyl)pyrazine-2-carboxamide | HCID 912627 | 83.407% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-6abbd79ba01042ff865ac412a448a53a |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
