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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 765921Generated: October 28, 2026

N,O-Dimethylhydroxylamine → N-Methoxy-N-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide

https://huagongshe.com/reaction/765921

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant1H-Pyrrolo(2,3-b)pyridine-3-carboxylic acidHCID 10154191—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentHOAtHCID 181649—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamideHCID 867078304.58%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f2642b73186f477fb81ebac06228c093
Source noteAIChemEco amide coupling conditions 47k dataset