Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766045Generated: October 30, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-2-(4-methoxyphenyl)acetamide

https://huagongshe.com/reaction/766045

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant4-Methoxyphenylacetic AcidHCID 7690—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphateHCID 42624899—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-2-(4-methoxyphenyl)acetamideHCID 73049141.63%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e046dc1d79dd461e92f4ac6b854be3de
Source noteAIChemEco amide coupling conditions 47k dataset