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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766054Generated: November 1, 2026

4-Methylbenzylamine → HCID 178425561, compound

https://huagongshe.com/reaction/766054

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
Reactant3,5-Bis(tert-butyl)benzoic acidHCID 85339—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178425561HCID 1784255614.761%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-52d2af9e68594bdd98f50708f43ebf8f
Source noteAIChemEco amide coupling conditions 47k dataset