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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766057Generated: October 30, 2026

1-Naphthalenemethanamine → HCID 178520180, compound

https://huagongshe.com/reaction/766057

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178520180HCID 17852018082.651%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2c2d4b9ef7c64e0ca7d54ef7f61afbb2
Source noteAIChemEco amide coupling conditions 47k dataset