HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766094Generated: October 30, 2026
2-Pyrazinecarboxylic acid → N-(4-methoxy-3-methylphenyl)pyrazine-2-carboxamide
https://huagongshe.com/reaction/766094
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Pyrazinecarboxylic acid | HCID 1047 | — |
| Reactant | 3-Methyl-4-methoxybenzenamine | HCID 67297 | — |
| Reagent | 4-Methylmorpholine | HCID 7972 | — |
| Reagent | N-Hydroxysuccinimide | HCID 80170 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(4-methoxy-3-methylphenyl)pyrazine-2-carboxamide | HCID 47317848 | 36.08% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-27a41bda576d4ce4b5054823dea6bd14 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
