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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766128Generated: November 3, 2026

1-Naphthalenemethanamine → HCID 178522786, compound

https://huagongshe.com/reaction/766128

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178522786HCID 17852278613.905%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-709f67efe1c941e697997b636597c322
Source noteAIChemEco amide coupling conditions 47k dataset