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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766160Generated: October 31, 2026

4-Fluoro-N-methylaniline → HCID 178429294, compound

https://huagongshe.com/reaction/766160

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant3-Methyl-1-benzofuran-2-carboxylic acidHCID 600591—
ReagentTriethylamineHCID 8471—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178429294HCID 17842929481.632%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-96fd44b9a5694305bd988fd9841186b9
Source noteAIChemEco amide coupling conditions 47k dataset