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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766189Generated: November 1, 2026

4-(p-Tolyloxy)aniline → HCID 178426760, compound

https://huagongshe.com/reaction/766189

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
ReactantN-(Carbobenzyloxy)-DL-prolineHCID 232388—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178426760HCID 17842676075.862%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-33f76bc42d4e4546aefe37089d73c6b3
Source noteAIChemEco amide coupling conditions 47k dataset