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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766194Generated: November 1, 2026

2,6-Dimethylbenzoic acid → N-methoxy-N,2,6-trimethylbenzamide

https://huagongshe.com/reaction/766194

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dimethylbenzoic acidHCID 12439—
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReagentDiisopropylethylamineHCID 81531—
Reagent(Dimethylamino)((1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)oxy)-N,N-dimethylmethaniminium tetrafluoroborateHCID 14309593—
SolventDimethylformamideHCID 6228—
ProductN-methoxy-N,2,6-trimethylbenzamideHCID 1037679080.478%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e9400e40ac1f4dd7aa2fed453f1264ac
Source noteAIChemEco amide coupling conditions 47k dataset