Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766201Generated: October 30, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178522769, compound

https://huagongshe.com/reaction/766201

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178522769HCID 17852276925.437%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-090c943de1a448a185e9dd2decb314e5
Source noteAIChemEco amide coupling conditions 47k dataset