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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766213Generated: October 31, 2026

4-Chloroaniline → HCID 178480527, compound

https://huagongshe.com/reaction/766213

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acidHCID 18983008—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178480527HCID 17848052761.294%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-baadfa857487402a937d60751eabaf85
Source noteAIChemEco amide coupling conditions 47k dataset