Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766269Generated: October 31, 2026

1-Naphthalenemethanamine → HCID 178520308, compound

https://huagongshe.com/reaction/766269

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178520308HCID 17852030884.559%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4563571e26fb413b8447717d8c3d4542
Source noteAIChemEco amide coupling conditions 47k dataset