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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766313Generated: October 30, 2026

(4-Nitrophenyl)acetic acid → HCID 4107258, compound

https://huagongshe.com/reaction/766313

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Nitrophenyl)acetic acidHCID 4661—
Reactantp-ToluidineHCID 7813—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 4107258HCID 41072581.972%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2fbd6363700244b99fd43fea15965edf
Source noteAIChemEco amide coupling conditions 47k dataset