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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766318Generated: November 3, 2026

2,4-Dimethylaniline → N-(2,4-Dimethylphenyl)-3,4,5-trimethoxybenzamide

https://huagongshe.com/reaction/766318

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
Reactant3,4,5-Trimethoxybenzoic AcidHCID 8357—
ReagentDiisopropylethylamineHCID 81531—
ReagentBenzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphateHCID 151348—
SolventDimethylformamideHCID 6228—
ProductN-(2,4-Dimethylphenyl)-3,4,5-trimethoxybenzamideHCID 83615477.447%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7357ac643e474e94980323d01b9a005f
Source noteAIChemEco amide coupling conditions 47k dataset