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HRID76635

反应详情

EQUATION

反应方程式

HRID 76635 的结构方程式

REACTANTS

反应物

2
结构：Nc1cccc(C(F)(F)F)c1
HCID7375

3-(Trifluoromethyl)aniline

C7H6F3N

结构：Fc1cnc(Cl)nc1Nc1ccc2c(c1)OCCO2
HCID22060362

未命名化合物

PRODUCTS

生成物

1
结构：Fc1cnc(Nc2cccc(C(F)(F)F)c2)nc1Nc1ccc2c(c1)OCCO2
HCID22060234

未命名化合物

PROCEDURE

实验过程

In like manner to the preparation of N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(3-hydroxyphenyl)-2,4-pyrimidinediamine, the reaction of 2-chloro-N4-(3,4-ethylenedioxyphenyl)-5-fluoro-4-pyrimidineamine with 3-trifluoromethylaniline gave N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(3-trifluoromethylphenyl)-2,4-pyrimidinediamine. LCMS: ret. time: 25.88 min.; purity: 89%; MS (m/e): 407 (MH+).

WORKUP

后处理

  1. customIn like manner to the preparation of N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(3-hydroxyphenyl)-2,4-pyrimidinediamine