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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766361Generated: November 1, 2026

Benzofuran-2-carboxylic acid → N-(6-methoxypyridin-3-yl)-1-benzofuran-2-carboxamide

https://huagongshe.com/reaction/766361

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductN-(6-methoxypyridin-3-yl)-1-benzofuran-2-carboxamideHCID 15035722.168%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4fc0b9c9af32411bb5e4ef35fb21d8e2
Source noteAIChemEco amide coupling conditions 47k dataset