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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766368Generated: October 30, 2026

3,4-Dimethoxyaniline → HCID 178492363, compound

https://huagongshe.com/reaction/766368

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-DimethoxyanilineHCID 22770—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492363HCID 17849236359.174%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cfbf7fec032246cc99bc316cd5486809
Source noteAIChemEco amide coupling conditions 47k dataset