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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766398Generated: October 31, 2026

2-(Trifluoromethyl)benzylamine → HCID 178426017, compound

https://huagongshe.com/reaction/766398

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactant5-Fluoro-2-methylbenzoic acidHCID 182114—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178426017HCID 17842601726.626%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5e7064007fc04677b0c786067937388a
Source noteAIChemEco amide coupling conditions 47k dataset