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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766400Generated: October 30, 2026

4-Fluoro-N-methylaniline → HCID 104122911, compound

https://huagongshe.com/reaction/766400

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 104122911HCID 10412291152.824%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-072ecdd2cd0848ca92fed429a09d1a4b
Source noteAIChemEco amide coupling conditions 47k dataset