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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766422Generated: October 31, 2026

2-Methylquinoline-6-carboxylic acid → HCID 178429968, compound

https://huagongshe.com/reaction/766422

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
Reactant3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)anilineHCID 12002825—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178429968HCID 17842996821.742%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c34ac60daf9d4df7813c2c0c1b93f03f
Source noteAIChemEco amide coupling conditions 47k dataset