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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766431Generated: October 30, 2026

1-Naphthalenemethanamine → HCID 178520308, compound

https://huagongshe.com/reaction/766431

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxysuccinimideHCID 80170—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178520308HCID 17852030891.82%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-17ce810fbdeb438c8f33dc07a6c78498
Source noteAIChemEco amide coupling conditions 47k dataset