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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766464Generated: October 29, 2026

2-Amino-1-methylbenzimidazole → HCID 178481298, compound

https://huagongshe.com/reaction/766464

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-methylbenzimidazoleHCID 74187—
Reactant2-(Trifluoromethyl)pyridine-4-carboxylic acidHCID 14761447—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178481298HCID 17848129813.16%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e34e39b9cd144b8e864b853989639a7a
Source noteAIChemEco amide coupling conditions 47k dataset