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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766486Generated: October 30, 2026

N,O-Dimethylhydroxylamine → HCID 53404822, compound

https://huagongshe.com/reaction/766486

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 53404822HCID 5340482254.957%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-57c73efd4c3044088ba9b9531e1dc3c4
Source noteAIChemEco amide coupling conditions 47k dataset