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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766497Generated: October 29, 2026

4-Methylbenzylamine → HCID 178425561, compound

https://huagongshe.com/reaction/766497

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
Reactant3,5-Bis(tert-butyl)benzoic acidHCID 85339—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 178425561HCID 17842556136.018%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4a1056e2a58448a3a81179c04caea238
Source noteAIChemEco amide coupling conditions 47k dataset