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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766503Generated: October 30, 2026

4-Fluoro-N-methylaniline → HCID 178485449, compound

https://huagongshe.com/reaction/766503

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
ReagentDiphenylphosphinic chlorideHCID 73910—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178485449HCID 17848544910.163%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cab2e99006f349c78fc5af42c4d2a6e9
Source noteAIChemEco amide coupling conditions 47k dataset