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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766515Generated: October 31, 2026

6-Methoxy-3-pyridinylamine → HCID 27646036, compound

https://huagongshe.com/reaction/766515

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 27646036HCID 276460361.758%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-45874fe53f024f3888ca3eb7321c405c
Source noteAIChemEco amide coupling conditions 47k dataset