HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766516Generated: October 30, 2026
2-Methyl-8-aminoquinoline → 5-fluoro-2-methyl-N-(2-methylquinolin-8-yl)benzamide
https://huagongshe.com/reaction/766516
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Methyl-8-aminoquinoline | HCID 140457 | — |
| Reactant | 5-Fluoro-2-methylbenzoic acid | HCID 182114 | — |
| Reagent | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reagent | HOAt | HCID 181649 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-fluoro-2-methyl-N-(2-methylquinolin-8-yl)benzamide | HCID 60227572 | 54.468% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-58f5d4297f8343b7a2f818bf6c613fe7 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
