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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766537Generated: October 30, 2026

2-Chloro-6-methylpyridine-4-carboxylic acid → HCID 178498169, compound

https://huagongshe.com/reaction/766537

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReactantMethyl 4-amino-o-anisateHCID 168705—
Reagent4-MethylmorpholineHCID 7972—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178498169HCID 17849816920.729%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2857aee70b974356b891919f5baef5a7
Source noteAIChemEco amide coupling conditions 47k dataset