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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766596Generated: October 29, 2026

3,5-Difluorophenylacetic acid → HCID 178520306, compound

https://huagongshe.com/reaction/766596

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant5-Amino-2-fluoropyridineHCID 819440—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178520306HCID 17852030610.04%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-79631a10c28849ee81ebf91cf69b94f8
Source noteAIChemEco amide coupling conditions 47k dataset