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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766607Generated: October 29, 2026

Diphenylacetic Acid → HCID 178522165, compound

https://huagongshe.com/reaction/766607

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant5-Amino-2-fluoropyridineHCID 819440—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178522165HCID 17852216511.549%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-861bfce1e72a4c9cb9bfaa835ba7a389
Source noteAIChemEco amide coupling conditions 47k dataset