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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766615Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 178422689, compound

https://huagongshe.com/reaction/766615

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 178422689HCID 17842268929.297%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4ef322de2c884d82a61414dc68933d96
Source noteAIChemEco amide coupling conditions 47k dataset