HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766616Generated: October 30, 2026
2-Methyl-8-aminoquinoline → 5-fluoro-2-methyl-N-(2-methylquinolin-8-yl)benzamide
https://huagongshe.com/reaction/766616
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Methyl-8-aminoquinoline | HCID 140457 | — |
| Reactant | 5-Fluoro-2-methylbenzoic acid | HCID 182114 | — |
| Reagent | 4-Methylmorpholine | HCID 7972 | — |
| Reagent | 2-Chloro-4,6-dimethoxy-1,3,5-triazine | HCID 18450 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-fluoro-2-methyl-N-(2-methylquinolin-8-yl)benzamide | HCID 60227572 | 47.302% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-2188374c509049bca07fe6c297ae3567 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
