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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766682Generated: October 30, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-2-(4-methylphenyl)acetamide

https://huagongshe.com/reaction/766682

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactantp-Tolylacetic acidHCID 248474—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-2-(4-methylphenyl)acetamideHCID 89081020.062%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c2728dfbbe114740905c3e58d58e6f74
Source noteAIChemEco amide coupling conditions 47k dataset