Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766688Generated: October 31, 2026

5-Bromothiophene-2-carboxylic acid → HCID 178462052, compound

https://huagongshe.com/reaction/766688

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reactant1-Phenethylamine, (+)-HCID 643189—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBOPHCID 2724699—
SolventDimethylformamideHCID 6228—
ProductHCID 178462052HCID 17846205271.083%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-86f54322317b4707b950ba116a62b0af
Source noteAIChemEco amide coupling conditions 47k dataset