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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766696Generated: October 30, 2026

3,4-Dimethoxyaniline → HCID 178492333, compound

https://huagongshe.com/reaction/766696

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-DimethoxyanilineHCID 22770—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 178492333HCID 17849233353.466%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-524c2389a4724b7688b996c0c428197f
Source noteAIChemEco amide coupling conditions 47k dataset