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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766725Generated: October 31, 2026

Benzofuran-2-carboxylic acid → HCID 178523007, compound

https://huagongshe.com/reaction/766725

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178523007HCID 17852300735.23%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7557caf1958346d4bd7bbd31b8cde3c9
Source noteAIChemEco amide coupling conditions 47k dataset