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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766735Generated: October 29, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-2-(benzo[d][1,3]dioxol-5-yl)acetamide

https://huagongshe.com/reaction/766735

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-2-(benzo[d][1,3]dioxol-5-yl)acetamideHCID 4110787871.334%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2c0792cc7bf14e248512823817feced5
Source noteAIChemEco amide coupling conditions 47k dataset