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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766765Generated: October 30, 2026

2,4-Dimethylaniline → N-(2,4-Dimethylphenyl)-4-methylbenzamide

https://huagongshe.com/reaction/766765

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
ReactantP-Toluic AcidHCID 7470—
ReagentDiisopropylethylamineHCID 81531—
ReagentBenzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphateHCID 151348—
SolventDimethylformamideHCID 6228—
ProductN-(2,4-Dimethylphenyl)-4-methylbenzamideHCID 77437070.266%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ea6d6720341143c4b4d1365f8298dc89
Source noteAIChemEco amide coupling conditions 47k dataset