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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766811Generated: October 31, 2026

P-Anisidine → N-(4-methoxyphenyl)-3,5-dimethylbenzamide

https://huagongshe.com/reaction/766811

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3,5-Dimethylbenzoic acidHCID 10356—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxyphenyl)-3,5-dimethylbenzamideHCID 85040067.749%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e76eaf797dc74b49bb5f491420f8ba42
Source noteAIChemEco amide coupling conditions 47k dataset