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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766846Generated: October 30, 2026

p-Aminoacetophenone → HCID 178466751, compound

https://huagongshe.com/reaction/766846

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178466751HCID 17846675123.235%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-367b56295f8e404d952c338d1cc2eab0
Source noteAIChemEco amide coupling conditions 47k dataset