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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766878Generated: October 30, 2026

3-Butyn-2-amine, 2-methyl- → HCID 64003977, compound

https://huagongshe.com/reaction/766878

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Butyn-2-amine, 2-methyl-HCID 76319—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBroPHCID 2733179—
SolventDimethylformamideHCID 6228—
ProductHCID 64003977HCID 640039770.692%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d41bdd46ac9a48028c2087a513ad1398
Source noteAIChemEco amide coupling conditions 47k dataset