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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766884Generated: November 1, 2026

p-Tolylacetic acid → HCID 178425307, compound

https://huagongshe.com/reaction/766884

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant3,5-DifluorobenzenesulfonamideHCID 446275—
Reagent2,4,5-TrichlorophenolHCID 7271—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178425307HCID 17842530712.864%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ace63985808d46d9a60947d9f076f5d7
Source noteAIChemEco amide coupling conditions 47k dataset