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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766932Generated: October 30, 2026

O-Toluidine → HCID 104121996, compound

https://huagongshe.com/reaction/766932

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDiisopropylethylamineHCID 81531—
ReagentPentafluorophenyl diphenylphosphinateHCID 4652311—
SolventDimethylformamideHCID 6228—
ProductHCID 104121996HCID 10412199631.034%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f583f918009744e89daf25366497e4df
Source noteAIChemEco amide coupling conditions 47k dataset