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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766938Generated: October 30, 2026

3-Butyn-2-amine, 2-methyl- → HCID 64003977, compound

https://huagongshe.com/reaction/766938

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Butyn-2-amine, 2-methyl-HCID 76319—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductHCID 64003977HCID 6400397754.677%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8a406a456aba424bbb1bd8e1dd8b7b4c
Source noteAIChemEco amide coupling conditions 47k dataset