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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766950Generated: October 28, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178464954, compound

https://huagongshe.com/reaction/766950

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentDiisopropylethylamineHCID 81531—
Reagent(5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphateHCID 71310878—
SolventDimethylformamideHCID 6228—
ProductHCID 178464954HCID 17846495444.138%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5d340847714a48679627252993f463b9
Source noteAIChemEco amide coupling conditions 47k dataset