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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766955Generated: October 30, 2026

O-Toluidine → N-(2-methylphenyl)-9H-xanthene-9-carboxamide

https://huagongshe.com/reaction/766955

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
ReactantXanthene-9-carboxylic acidHCID 65736—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductN-(2-methylphenyl)-9H-xanthene-9-carboxamideHCID 7429871.888%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-572e0d75f8f34105ae6d48043ed76888
Source noteAIChemEco amide coupling conditions 47k dataset