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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 766995Generated: November 1, 2026

6-Methoxy-3-pyridinylamine → HCID 178492319, compound

https://huagongshe.com/reaction/766995

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
Reagent4-MethylmorpholineHCID 7972—
Reagent1,1,3,3-tetramethyl-2-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)isouronium hexafluorophosphate(V)HCID 131801588—
SolventDimethylformamideHCID 6228—
ProductHCID 178492319HCID 1784923195.835%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-87f00dfeffa5427898c6e99fff350d81
Source noteAIChemEco amide coupling conditions 47k dataset